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Next-wave candidates like ET-02 and VDPHL01 are advancing in human trials, with potential to add pigment restoration and oral convenience

Natural products from plants, fungi, and marine sources show diverse bioactivities, while phytochemicals including flavonoids, alkaloids, terpenoids, polyphenols, tannins, and glycosides demonstrate anti-inflammatory, antioxidant, antimicrobial, immunomodulatory, and mucosal-protective effects

Glutathione, as a potent antioxidant, helps neutralize free radicals, reducing oxidative damage to the skin cells

M., Crowell, M

Effect of chronic periodontitis on oxidative status in patients with rheumatoid arthritis